Protective effect for prostate
Recent clinical trials have shown that vitamin D and its analogues may be an important factor in the treatment of prostate cancer. The data from the experiments indicate that the active form of vitamin D inhibits proliferation, spread and metastasis of prostate cancer cells by separating cell division. Scientists have examined the links between sun exposure and prostate cancer. They compared 450 men with advanced prostate cancers to 450 men without cancer. They found that the subjects who benefited the most from the sun had a 50% lower risk of prostate cancer than those who had less sun exposure. Experts, the sun, by increasing vitamin D synthesis protects men from prostate cancer, they think. Considering the current links between the sun and certain types of skin cancer, they conclude that vitamin D intake should be increased through food supplements and nutrition.
Another study has shown that vitamin D can play a therapeutic role after prostate cancer has developed. Sixteen men who had previously been treated for prostate cancer were given 2,000 IU daily vitamin D supplementation, and the subjects’ prostate-specific antigen values (PSA, marking the recurrence or progression of prostate cancer) were continuously monitored for 2 years. Nine patients had decreased or remained PSA values after starting vitamin D food supplementation. In patients whose values continue to increase, food supplementation has slowed down the doubling of values by 75% (the increase or doubling of PSA is closely linked to the course of the disease. The longer the doubling value, the better the results). The results suggest that vitamin D can prevent or slow the recurrence or spread of the disease in patients receiving prostate cancer treatment.
Vitamin D deficiency weakens the immune system
Scientists associate immune system health with vitamin D3 deficiency in various aspects. Vitamin D3 regulates T lymphocytes, which are crucial for the robust functioning of the immune system. Peptides stimulated with vitamin D3 have a major role in protecting the lungs from infections. Vitamin D3 deficiency also leads to the development and spread of various autoimmune diseases.
A published scientific paper on this subject has provided important evidence that seasonal infections, such as influenza, may not be due to the traditional increase in viral activity, but to the decrease in vitamin D3 concentrations in winter.
Vitamin D receptors are found in most cells of the immune system that eliminate viruses and bacteria. As a result, vitamin D, which is limited in nature due to the lack of sun in winter, is a necessary substance for the cells to activate correctly.
Positive effect in case of heart failure
Heart failure or the inability of the heart to pump enough blood to meet the needs of the organism are among the main causes of death in industrialized countries. Scientists believe that elevation of cytokine values that support infection in the circulatory system may increase heart failure, and vitamin D can suppress them and provide positive protection.
In a double-blind trial (a type of controlled research / experimental technique in which neither the researcher or the subjects participated, nor the persons performing the research or experiment did not know the main purpose of the study or who was in the control group, who was in the control group), 123 patients diagnosed with congestive heart failure for nine months During the study, 2000 IU of vitamin D and 500 mg of calcium or a placebo and 500 mg of calcium were administered daily by random grouping. In patients receiving vitamin D supplementation, it was observed that the value of interleukin, an anti-inflammatory cytokine, was clearly increased and that the tumor necrosis factor, an inflammation-promoting cytokine, decreased. Scientists believe that vitamin D can be a promising treatment for patients diagnosed with congestive heart failure by reducing the factors that support infection.
Can help prevent diabetes
Vitamin D has the ability to reduce the susceptibility to Type 2 diabetes by slowing down the decrease in insulin sensitivity of patients presenting with preliminary symptoms of diabetes. The researchers followed 314 undiagnosed adults for three years daily with 700 IU of vitamin D and 500 mg of calcium. At the beginning of the study, food supplementation in people with slightly elevated blood glucose values on an empty stomach slowed the rise in blood glucose values and stopped the increase in insulin resistance compared to other subjects. Thus, researchers concluded that food supplements for elderly people with high blood sugar values can help prevent metabolic syndrome and diabetes.
Preventing the fall of the elderly
Frequent falls in the elderly cause significant damage and death. Research suggests that vitamin D may be useful in preventing it. Indeed, the results of some cross-studies have shown that elderly people with high levels of vitamin D in their blood fall less. According to a meta-analysis (a statistical method to determine whether there are significant trends by combining the findings from several separate, similar, generally published studies conducted by independent researchers), the dietary supplement with vitamin D was reduced by 22%. decreased. Another controlled trial revealed that a three-month food supplement with 1200 mg of calcium and 800 IU of vitamin D3 daily reduced the risk of falling elderly people in nursing homes by 49%.
Safety of vitamin D
Vitamin D is generally well tolerated by adults up to a dose of 2000 IU per day. Some studies even point out that vitamin D can be used without risk for up to 10,000 IU per day, while official health institutions have established a safe daily dose of vitamin D at 1000 IU. This is the result of a team of 21 investigations and clinical trials conducted in humans with doses well above the officially recommended dose. Afssa, the French Food Agency says that a daily dose of 200 IU in healthy adults and a dose of 400 IU to 600 IU in the elderly is sufficient to stay healthy, while scientists say that the daily requirement is around 1000 IU.